Cdh16 cre小鼠

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August undefined, 2024

WebApr 5, 2014 · 目前已有的PEPCK-cre工具鼠仅有Hprttm1(Pck1-cre)Vhh变型启动子使肝中cre表达降低60%，而肝中cre表达提高10倍。同时需注意此工具鼠中同时敲除了Hprt基 … WebAug 1, 2024 · Cre 工具鼠的种类及应用 Cre 工具鼠主要分为 3 类：全身性 Cre、组织特异性 Cre 和配体或药物诱导 Cre。全身性 Cre：通过诱导剂来调节驱动 Cre 重组酶的启动子活 …

CDH16 Gene - GeneCards CAD16 Protein CAD16 …

WebMacrophages are specialized phagocytes that display a variety of important functions for the host immune system. They are particularly important for the recognition of exogenous and endogenous danger signals, forming the defensive front line as part of innate immune response. As such, murine macroph … WebFeb 24, 2016 · In aged Cdh16-Cre;Sav1 fl/fl mice, we observed focal disruption of proximal tubules and perivascular lymphocytic infiltration. In conclusion, Sav1 is required for the maintenance of growth, nuclear size and structure of renal tubules under physiological conditions, and its deficiency leads to the acquisition of enhanced proliferation of renal ... find next in progress 4gl

IL-23 reshapes kidney resident cell metabolism and promotes …

http://geneandpeace.com/index.php?m=home&c=View&a=index&aid=178 Web在Cdh16基因目的exons两侧分别插入loxP位点。该flox小鼠可与组织特异性Cre工具鼠交配,获得在特定细胞类型或组织中敲除Cdh16基因的小鼠模型。 Web视觉中国旗下网站（vcg.com）通过麦穗图片搜索页面分享：麦穗高清图片，优质麦穗图片素材，方便用户下载与购买正版麦穗图片，国内独家优质图片，100%正版保障，免除侵权 … eric clothes

Cre 小鼠大百科：什么是 Cre 工具鼠？_公司新闻_丁香通

WebCre 蛋白是一种重组酶，是causes recombination的缩写，于1981 年从 P1 噬菌体中被发现，属于 λInt 酶超基因家族。Cre 重组酶基因编码区序列全长1029bp，编码 38kDa 蛋白 … WebMar 21, 2024 · CDH16 (Cadherin 16) is a Protein Coding gene. Diseases associated with CDH16 include Oncocytoma and Eosinophilic Variant Of Chromophobe Renal Cell Carcinoma.Among its related pathways are … findnext in beautiful soupWeb8 Nestin 启动子驱动Cre 转基因小鼠（Nestin-Cre） 9 诱导性全身表达Cre 转基因小鼠UBC-cre/ESR1 10 细胞特异Cre 转基因小鼠Lck-cre 11 MX1-Cre 转基因小鼠 12 脑组织特异Cre 转基因小鼠 Carp-cre 13 B6.129(Cg)-Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/J 14 单核细胞特异Cre 小鼠 Lyz2-Cre find next icon

"Web如果有多种不同的 Cre，那么就需要分别表示。例如：Tlr5 flox 小鼠分别与小肠上皮细胞（IEC）特异性 Cre(Vil-Cre)、DC 细胞特异性 Cre(CD11c-Cre) 交配的子代中发生基因 … " - Cdh16 cre小鼠

Cdh16 cre小鼠

Tg(Cdh16-cre)91Igr Transgene Detail MGI Mouse …

Web图1. Cre-Lox基因重组系统工作原理[2] 利用Cre-Lox系统如何制备条件性敲除小鼠. Cre-Lox系统的优势在于可以利用组织特异性启动子特异性控制Cre在特定组织的表达，以实现在特 … http://www.xjishu.com/zhuanli/27/202411058227.html

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Web南模生物自主研发p53条件性基因敲除小鼠模型（p53-CKO），可与组织特异性Cre工具鼠交配，获得特定组织或细胞中p53纯合缺失小鼠，用于肿瘤发生、机制研究。 ... 例如： … http://www.labmodel.cn/mod_product-view-p_id-4168.html

WebCN108467871B CN202410133033.1A CN202410133033A CN108467871B CN 108467871 B CN108467871 B CN 108467871B CN 202410133033 A CN202410133033 A CN 202410133033A CN 108467871 B CN108467871 B CN 108467871B Authority CN China Prior art keywords mouse gene kidney promoter constructing Prior art date 2024-02-09 … Web血管内皮细胞特异性cre工具小鼠. 实验动物背景信息. C57BL/6. 模型制作方法. 转基因. 模型表型数据. 通过研究发现，Cdh5-cre 成年小鼠中，所有受检器官的血管和血管内皮细胞 …

http://www.informatics.jax.org/allele/MGI:3641108 WebNov 22, 2024 · 图1a中示出，先将基因公司交付给申请人的brd4 f/f 小鼠与商购的携带cdh16 ‑ cre酶的工具小鼠相交配，得到“brd4 f/ ‑,cdh16 ‑ cre小鼠”，该小鼠中cdh16 ‑ cre基因呈 …

WebCre基因前，使其启动Cre酶的表达，从而介导lox 位点问特定基因DNA片段的敲除，当敲除过程完成后，DNA片段重新结合，形成一个lox位点。

WebCre 蛋白是一种重组酶，是causes recombination的缩写，于1981 年从 P1 噬菌体中被发现，属于 λInt 酶超基因家族。Cre 重组酶基因编码区序列全长1029bp，编码 38kDa 蛋白 … eric clopper harvardWebMar 21, 2024 · CDH16 (Cadherin 16) is a Protein Coding gene. Diseases associated with CDH16 include Oncocytoma and Eosinophilic Variant Of Chromophobe Renal Cell Carcinoma. Among its related pathways are … eric clothes shoppingWebTransgene Type: Transgenic (Inducible, Recombinase) Inducer: tamoxifen. Mutation: Insertion. Mutation details : The transgene consists of 1.4 kb fragment of the murine Cdh16 5' promoter region and a tamoxifen-inducible form of cre recombinase. Inducible Cre activity is seen in renal tubular epithelial cells and collecting ducts. eric clinics arrestedWebMay 6, 2024 · All mice were Cdh16-cre +. Cells were stimulated with IL-23 or PBS for 48 hours for Western blots ( D ) and quantification ( E ) of the expression of the indicated proteins. ( F ) Flow cytometric analysis of in vitro proliferative response (CFSE lo ) to anti-CD3 plus anti-CD28 of purified splenic CD4 + T cells cocultured 72 hours with the ... eric clyde copenhaverWebTransgenic cre activity, directed by the mouse aquaporin 2 promoter, is observed in kidney cells (collecting duct, left) and testes (sperm, right). 010774. B6(Cg)-Calb2 tm1(cre)Zjh /J. Calb2, calbindin 2. Cre activity is expected in calretinin interneurons in the brain and cortex driven by the endogenous Calb2 promoter/enhancer elements. 005359 find next in excelhttp://www.labmodel.cn/mod_product-view-p_id-4167.html eric cloud hammons arrestedWebOct 10, 2024 · Methods. Cdh16-Cre tool mice and Kindlin-2 flox/flox mice were used to construct the mouse model of uterus specific knockout of Kindlin-2, and the effects of Kindlin-2 deletion on uterine development and reproduction capacity of female mice were observed. High expression and knockdown of Kindlin-2 in endometrial cancer cell lines … eric cloud hammons arrested ga