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Fsh receptor antibody

WebSignificance. We report the development and characterization of a first-in-class humanized antibody to follicle-stimulating hormone (FSH). We have shown previously that … WebFollicle-Stimulating Hormone Receptor (FSHR) expression has been reported in ovary, uterus, and testis. ESTs have been isolated from testis …

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WebFSH receptor is a G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. Application Notes: To test if the antibody dependent cellular cytotoxicity elicited by the mouse version of this antibody translated into an in vivo anti ... WebOct 30, 2024 · Injecting FSH specific antibodies in pregnant hamsters resulted in significant reduction in PF numbers (2.4% vs 25%) which could be reversed by injecting eCG (18%). ... Kramer EE, Chen YT. Follicle-stimulating hormone receptor is expressed in human ovarian surface epithelium and fallopian tube. Am J Pathol. 1996;148(1):47–53. CAS … property for sale in oregon city https://safeproinsurance.net

Blocking FSH inhibits hepatic cholesterol biosynthesis and reduces ...

WebOct 8, 2012 · Model of the signaling pathway by which FSH promotes AKT activation in GCs. FSH binding to and activation of the FSH G protein-coupled receptor leads to activation of the stimulatory G protein (G s), activation of adenylyl cyclase (AC), generation of cAMP, and activation of type I PKA (R I 2 C 2).PKA directly (unbroken line) or … Web保存条件: CGA/HCG-α Rabbit Monoclonal Antibody -20ºC保存,需避免反复冻融。Western一抗稀释液-20℃或4℃保存,一年有效,Western一抗稀释液优先推荐4℃保存,长期不使用可以考虑-20℃保存,但冻融可能会导致出现轻微的浑浊和少量不溶物。 WebOct 18, 2024 · Background: The follicle-stimulating hormone (FSH)-receptor (FSHR) has been reported to be an attractive target for antibody therapy in human cancer. However, … property for sale in oreston plymouth

Follicle-stimulating hormone receptor - Wikipedia

Category:Anti-FSHR Antibodies Invitrogen - Thermo Fisher Scientific

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Fsh receptor antibody

Thyrotropin receptor antibodies: new insights into their …

WebAll lanes : Anti-FSH-R antibody (ab75200) at 1/500 dilution Lane 1 : Transfected Jurkat cell extract Lane 2 : Transfected HUVEC cell extract Lane 3 : Transfected Jurkat cell extract … WebMar 6, 2024 · FSHβ Antibody (C-12) is a mouse monoclonal IgG 2b κ FSHβ antibody, cited in 3 publications, provided at 200 µg/ml; raised against amino acids 48-129 mapping at the C-terminus of FSHβ of human origin; FSH beta Antibody (C-12) is recommended for detection of FSHβ of mouse, rat and human origin by WB, IP, IF and ELISA

Fsh receptor antibody

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WebAliquot and store at -1041°C long term. Avoid freeze-thaw cycles. Research Use Only. For research use only. Target. Target. FSHR. Alternative Names. Follicle-stimulating … WebThe antibodies were shown to be monospecific for the FSH receptor by the following three independent methods: immunoblotting of cell extracts from ovarian specimens and of lysates of cell cultures ...

WebSep 4, 2012 · Here, we generated and characterized a polyclonal antibody to a 13-amino-acid-long peptide sequence within the receptor-binding domain of the FSH β-subunit. We show that the FSH antibody binds FSH specifically and blocks its action on osteoclast formation in vitro. When injected into ovariectomized mice, the FSH antibody attenuates … WebThe follicle-stimulating hormone receptor or FSH receptor (FSHR) is a transmembrane receptor that interacts with the follicle-stimulating hormone (FSH) and represents a G protein-coupled receptor (GPCR). Its activation is necessary for the hormonal functioning of FSH. ... Antibodies to FSHR can interfere with FSHR activity. FSH abnormalities

WebThe anti-FSH receprot antibody ab11321 was raised against an immunogen located between residues 280 and 330 of human FSHR. Refering to the SwissProt reference P23945, this entire region is located within the N-terminal extracellular domain of the … WebBoster Bio Anti-FSH Receptor/FSHR Antibody Picoband™ catalog # A00897. Tested in WB applications. This antibody reacts with Human, Mouse. Supplied as 100μg/vial in Lyophilized form antibody.

WebFeatured Products. Human, Monkey, Rat, Bat, Bovine, Goat, Horse, Pig, Rabbit, Sheep. FSH Receptor / FSHR Antibody (clone 12K98) LS‑C182856. Human. Applications: IHC. Human. 0.313-20 ng/ml. See all …

WebOct 21, 2010 · The antibodies were shown to be monospecific for the FSH receptor by the following three independent methods: immunoblotting of cell extracts from ovarian specimens and of lysates of cell cultures ... property for sale in orihuela spainWebAll lanes : Anti-FSH-R antibody (ab75200) at 1/500 dilution Lane 1 : Transfected Jurkat cell extract Lane 2 : Transfected HUVEC cell extract Lane 3 : Transfected Jurkat cell extract with immunising peptide at 10 µg Lysates/proteins at 10 µg per lane. Predicted band size: 78 kDa Observed band size: 78 kDa Additional bands at: 85 kDa. We are unsure as to the … property for sale in orma wvWebNov 17, 2024 · Protein thermal shift, molecular dynamics, and fine mapping of the FSH-FSH receptor interface confirm stable binding of the Fab domain to two of five receptor … lady knight frey rpgWebMay 24, 2024 · Here, we report that this antibody sharply reduces adipose tissue in wild-type mice, phenocopying genetic haploinsufficiency for the Fsh receptor gene Fshr. The … property for sale in orlingbury northantsWebDec 17, 2024 · The function of FSH is mainly mediated through FSH receptors (FSHRs). 14 FSHR is a transmembrane receptor that interacts with FSH and is a G protein-coupled receptor (GPCR). 20 Published data ... property for sale in oregon owner carryWebThe protein encoded by this gene belongs to family 1 of G-protein coupled receptors. It is the receptor for follicle stimulating hormone and functions in gonad development. Mutations in this gene cause ovarian dysgenesis type 1, and also ovarian hyperstimulation syndrome. Alternative splicing results in multiple transcript variants. property for sale in orland park ilWebAug 24, 2024 · Background: The follicle-stimulating hormone (FSH)-receptor (FSHR) has been reported to be an attractive target for antibody therapy in human cancer. ... FSHR323 was the only antibody to detect ... property for sale in orofino idaho